Maru Shital Mahindra Publications | ||||
1 | 2015 | Formulation And Evaluation Of Ibuprofen Gel Using A Natural Polymer Click to View Abstract
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2 | 2014 | Risk Factors And Management Of Stress Ulcers In The Critical Care Unit In A Kenyan Referral Hospital Click to View Abstract
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3 | 2013 | Formulation Development Of Sustained Release Zidovudine-lamivudine Fixed Dose Combination Paediatric Mini Matrices By Hot Melt Extrusion Click to View Abstract HIV/AIDS has become one of the major and deadliest pandemics in the world today. Besides This study was therefore designed to investigate the physicochemical properties of | ||
4 | 2012 | In-Vitro Drug Release Studies To Compare The Release Of Metronidazole Topical Formulations Through Cellulose Membrane.East And Central African Journal Of Pharmaceutical Science. Vol 15 (3) (2012). Click to View Abstract
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5 | 2009 | Shital M.Maru, Marcel DeMatas, Adrian Kelly, Anant Paradkar. Characterisation Of Rhelogical And Thermal Properties Of Zidovudine, Lamivudine And Ethylcellulose Blends To Assess Their Suitability For Hot Melt Extrusion. Journal Of Pharmacy And Pharmacology Click to View Abstract Normal 0 false false false MicrosoftInternetExplorer4
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Hepatocellular carcinoma results when cancerous cells are localized in the liver. It is distributed globally with high prevalence in sub-Saharan African, southern Asia, China and Japan. Diagnosis is experimental and in many cases inaccurate due to unreliability of markers. Prognosis is poor and the cost of treatment prohibitive. Conventional radiation and chemotherapy lead to loss of hair, fertility and general weakening of the body`s immune system increasing a patient`s risk to infection. These observations underscore the need for improved, or additional methods of cancer diagnosis and management. We investigated the effect of polysaccharide rich Pleurotus pulmonarius fruit body extracts on progression of chemically induced hepatocellular carcinoma in CBA mice. Addition of Pleurotus pulmonarius extracts in diet delayed progression of carcinogenesis suggesting that these extracts may be useful as adjuvants to conventional cancer therapies.
Key words: carcinogenesis; mice; mushroom extracts; pleurotus pulmunarius
Corresponding author: Ms Carolyne Wasonga, Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya. E-mail: carox27@yahoo.ca
Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Hans-R Tinneberg, Timothy K. Roberts. IS OVINE PLACENTAL IGG TOXIC TO HUMAN PERIPHERAL BLOOD NATURAL KILLER CELLS? | ||
6 | 2006 | P.N. Karimi, S.M. Maru, J.M. Bururia, K.A.M. Kuria And P.A. Odhiambo (2006). Prevalence And Antimicrobial Susceptibility Of Staphylococcus Aureus At The Kenyatta National Hospital, Nairobi. East Centr. Afr. J. Pharm. Sci.9:71-73. Click to View Abstract A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients. | ||
7 | 2005 | S. Maru And F.V. Manvi (2005). Formulation And Evaluation Of Tenoxicam Topical Gels. The East And Central African Journal Of Pharmaceutical Sciences, 8:14 Click to View Abstract A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients. | ||
8 | 2005 | S. Maru (2005). Formulation And Evaluation Of Tenoxicam Niosomes. The East And Central African Journal Of Pharmaceutical Sciences, 8:62 Click to View Abstract A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients. | ||
9 | 2003 | Substance Use Among Children And Young Persons Appearing In The Nairobi Juvenile Court, Kenya Click to View Abstract To estimate the prevalence and pattern of substance use among children and young persons appearing in the Nairobi Juvenile Court, Kenya. DESIGN: A point prevalence survey. SETTING: The Nairobi Juvenile Court, Kenya. SUBJECTS: Ninety (sixty four males and twenty six females) children and young persons aged 8 to 18 years classified as criminal offenders, group I (60) and those for protection and discipline, group II (30), were selected. METHOD: Socio-demographic and substance use questionnaires were administered to the subject. International classification of diseases, 10th Edition (ICD-10) diagnostic criteria were used. RESULTS: Crude rate for substance use in this study was found to be 39 out of the total sample of 90(43.3%), children and young persons. Of these thirty nine, 33 (85.8%) were males and six(14.2%) were females. Twenty nine (32.2%) used nicotine, 19(21.1%) used volatile hydrocarbons, 8(8.9%) used cannabis six (6.7%) used alcohol, five (5.6%) used khat and three (3.3%) used sedatives. Multiple substance use was also evident. CONCLUSION: This study has shown a high presence of substance use in children and young persons appearing in the Nairobi Juvenile Court. | ||
10 | 2003 | Psychiatric Morbidity Among Children And Young Persons Appearing In The Nairobi Juvenile Court, Kenya Click to View Abstract To estimate the prevalence and pattern of psychiatric disorders among children and young persons appearing in the Nairobi juvenile court, Kenya. DESIGN: A point prevalence survey. SETTING: The Nairobi Juvenile Court, Kenya. SUBJECTS: Ninety (sixty-four males and twenty-six females) children and young persons aged 8 to 18 years classified as criminal offenders, group I (60), and those for protection and discipline, group II (30), were selected. METHOD: A socio-demographic questionnaire, reporting questionnaire for children (RQC), follow-up interview for children (FIC), present state examination (PSE) and clinical interview were administered to the subjects. International Classification of Diseases, 10th Edition (ICD-10) diagnostic criteria were used. RESULTS: The crude psychiatric morbidity (CPM) rate was 44.4%. ICD-10 documented psychiatric disorders detected in those with CPM were conduct disorders 45%, mixed disorders of conduct and emotion 20%, emotional disorders with onset specific to childhood 20%, mood disorders 12.5% and hyperkinetic disorders 2.5%. CONCLUSION: This study has shown a high presence of psychiatric morbidity in children and young persons appearing in the Nairobi Juvenile Court. These juveniles need and would benefit from mental treatment as recommended in section 18 of Cap 141 of the laws of Kenya; The Children's and Young Persons Act |
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