Prof. Oliech Joseph S Publications | ||||
1 | 9999 | Medical Treatment On Bening Prostatic Hyperplasia (BPH) With Combination Drug Therapy. Click to View Abstract Obective:To carry out an overview of the medical treatment of the benign prostatic hyperplasia using the combination drugs of alpha adrenergic uro-selective blockers(tamsulocin,alfuzocin) and the 5 alpha reductase iso-enzymes 1&2 inhibitor dutasteride . Data source :Review of researches don and those ongoing especially those sponsored and financed by GlaxoSmithcline in the multicenter international control trials. Data selction: Selected data from international researches on BPH from the following research groups MTOPS,PREDICT,PLESS,VCOOP,ALFIN,DUTASTERIDE 4-DATA 2004/PHASE 111a studies,COmbAT2007,SMART-1, also from GlaxoSmithkline data files.Data Extraction:Selection of research conclusions from various researches tested for clinical use by the international researchers.Data synthesis:From these the advantages of drug compliance on clinical use on BPH was analysed. | ||
2 | 9999 | WATER,HUMAN HEALTH/WELLNESS Click to View Abstract Scientific paper presented during the FIFTH ANNUAL REGIONAL WORKSHOP ON THE THEME;`` WATER IS LIFE``. Abstract: The paper illustrates the health status of water in the human body in health and in disease situations and how body water content depends on many variables including age, sex, fat content,leaness of muscles ,the internal environment of body cells and the external envronmental air and temperature. | ||
3 | 9999 | { Training Of A Urological Surgeon (Editorial}. Medicom 4:3, 1982 Click to View Abstract n/a | ||
4 | 2013 | UNUSUAL CAUSE OF ACUTE URINARY RETENTION (AUR) COLORECTAL ADENOCARCINOMA, METASTATIC TO URINARY BLADDER: CASE REPORT Click to View Abstract A 72 year old African male presented with a 2 weeks history of haematurla with clots, dysuria, nocturia, frequency and subsequently 2 day history of acute urinary retention (AUR). There were no colonic symptoms of mucus discharge, blood per rectum or malaena stools. Imaging studies demonstrated a tumour mass invading the roof of the urinary bladder whilst cyctoscopic finding were inconclusive. Following surgical intervention, the mass was subjected to histopathological evaluation which confirmed colonic adenocarcinoma matastasis in the urinary bladder. It is now 4 ½ years since surgery was carried out and follow up shows good prognosis. | ||
5 | 2012 | Symptomatic And Uroflometry Outcomes Of Tamsulosin And Dutasteride Combination In Management Of Benign Prostatic Hypertrophy In The Black Race Click to View Abstract Objective: Benign prostatic hyperplasia (BPH) incidence and progression has been shown to vary by race, geography and ethnicity with African-Americans having a more aggressive disease than other races. Combination drug therapy has been shown to be a favorable option for medical therapy of symptomatic BPH but data is lacking on the effects of this therapy in black race patients locally. This study aims to assess the early (six months) response, by both International-Prostate Symptom Score (IPSS) and peak urinary flow rate (QMax), to combination drug therapy of Tamsulosin and Dutasteride for management of symptomatic BPH in a predominantly African black race population cohort as a pilot study. | ||
6 | 2010 | Combination Drug Treatment Of Beingn Prostatic Hyperplasia (BPH) Click to View Abstract Combination use of alpha-adrenergic blockers (tamsulocin or alfuzocin) and 5 alpha iso-enzyme 1&2 inhibitor (dutasteride) in symptomatic benign prostatic hyperplasia (BPH) is the best first optional mode of treatment giving good results with minimal treatment adverse effects especially for those at risk for surgical intervention and those who are still sexually active. | ||
7 | 2007 | Treatment Of Benign Prostatic Hyperplasia At Mater Hospital, Nairobi. Click to View Abstract OBJECTIVE: To evaluate the use of medical therapy in the management of patients with mild, moderate and severe symptoms of benign prostatic hyperplasia. DESIGN: Prospective study. SETTING: Private urology clinic in Mater Hospital, Nairobi between 1995 and 2005. PATIENTS: Six hundred and eighty patients with benign prostatic hypertrophy aged 50-80 years. RESULTS: Two hundred and eighty (43.8%) patients benefited from the drug treatment alone and were released from the clinic follow up after five years. Two hundred and seventy (42.2%) cases could not complete the five years follow up on drugs alone due to symptoms recurrence or severity or unavailability of drugs. They were removed from the drugs alone treatment and put on other interventions. Ninety (15.9%) cases were operated on based on their decision and insistence or severity of their symptoms or no drugs response. CONCLUSIONS: This observational study confirms that medical treatment is beneficial in the management of benign prostatic hyperplasia (BPH) and is cheap and gives better first line option of treatment choice to many patients. It also gives hopes to the surgical risk patients. The quality of life (QOL) of patients and their family disturbance is also improved. | ||
8 | 2005 | Outcome Of Moderate And Severe Thermal Injuries At Kenyatta National Hospital Click to View Abstract Background: Thermal injuries are a major cause of morbidity and mortality in Kenya. Though a lot is known about burns, the morbidity patterns and mortality rates of burns in this country have not been established. This study was designed with the general objective of investigating the outcome of moderate and severe burns managed at the Kenyatta National Hospital (KNH). It was also the aim of the authors to try to validate an existing simple clinical burn injury score, based on the Abbreviated Burn Severity Index (ABSI) score. | ||
9 | 1998 | Renal Stones Click to View Abstract OBJECTIVE: To evaluate the use of medical therapy in the management of patients with mild, moderate and severe symptoms of benign prostatic hyperplasia. DESIGN: Prospective study. SETTING: Private urology clinic in Mater Hospital, Nairobi between 1995 and 2005. PATIENTS: Six hundred and eighty patients with benign prostatic hypertrophy aged 50-80 years. RESULTS: Two hundred and eighty (43.8%) patients benefited from the drug treatment alone and were released from the clinic follow up after five years. Two hundred and seventy (42.2%) cases could not complete the five years follow up on drugs alone due to symptoms recurrence or severity or unavailability of drugs. They were removed from the drugs alone treatment and put on other interventions. Ninety (15.9%) cases were operated on based on their decision and insistence or severity of their symptoms or no drugs response. CONCLUSIONS: This observational study confirms that medical treatment is beneficial in the management of benign prostatic hyperplasia (BPH) and is cheap and gives better first line option of treatment choice to many patients. It also gives hopes to the surgical risk patients. The quality of life (QOL) of patients and their family disturbance is also improved. | ||
10 | 1998 | Clinical Presentation And Management Of Renal Cell Carcinoma. Click to View Abstract A study of clinical presentation and management of renal cell carcinoma (RCC) in 35 patients during the period 1983 to 1997 is presented. The peak age was 40-50 years. Haematuria, abdominal pain, fever of unknown origin and abdominal mass were the commonest presenting features. Computerised tomographic (CT) scanning, intravenous urography (IVU) and magnetic resonance imaging (MRI) were the important diagnostic tools. Early diagnosis and surgery are the most important approaches in management. | ||
11 | 1998 | Urinary Tract Stone Disease In Nairobi. Click to View Abstract At the Kenyatta National Hospital (KNH) and other private hospitals in Nairobi urinary stone disease is not being correctly diagnosed. Over a 15 year period (1980-1995) only 56 patients have been confirmed to have urinary tract stones out of the expected number of 220 patients. The age range was 10-60 years. The peak age was 30-40 years. Pain and haematuria were the commonest presenting symptoms. Ultrasonography and plane abdominal radiology were the commonest methods of diagnosis. Open surgery and endoscopic stone removal were the commonest modes of management. Extracorporeal shortwave lithotripsy (ESWL) has recently been introduced into the Nairobi Hospital, but was not functional at the time of this study. Percutaneous nephrolithotomy (PCNL) is possible but has not been adequately used due to lack of correct equipment. Septicaemia and haemorrhage were the commonest complications of the open surgery. | ||
12 | 1998 | Urinary Tract Stone Disease In Nairobi Click to View Abstract At the Kenyatta National Hospital (KNH) and other private hospitals in Nairobi urinary stone disease is not being correctly diagnosed. Over a 15 year period (1980-1995) only 56 patients have been confirmed to have urinary tract stones out of the expected number of 220 patients. The age range was 10-60 years. The peak age was 30-40 years. Pain and haematuria were the commonest presenting symptoms. Ultrasonography and plane abdominal radiology were the commonest methods of diagnosis. Open surgery and endoscopic stone removal were the commonest modes of management. Extracorporeal shortwave lithotripsy (ESWL) has recently been introduced into the Nairobi Hospital, but was not functional at the time of this study. Percutaneous nephrolithotomy (PCNL) is possible but has not been adequately used due to lack of correct equipment. Septicaemia and haemorrhage were the commonest complications of the open surgery | ||
13 | 1996 | Renal Vein And Intracaval Invasion By An Adrenal Phaechrocytoma With Extension Into The Right Atrium. Click to View Abstract A 30 year old female with an unexpected right adrenal phaechromacytoma invading the renal vein, the inferior vena cava and extending into the right atrium is presented. She also had BuddChiari syndrome due to invasion of the hepatic veins by the tumour. Additionally, the tumour had metastasised to the liver and the lungs. Despite elevated 24 hour urinary vanillylmandelic acid (VMA) the patient was normotensive pre-operatively. The patient underwent right adrenalectomy and extended nephrectomy with milking of the tumaur from the inferior vena cava. Unfortunately, the patient developed multiple hypotensive episodes and adult respiratory distress syndrome post-operatively and died three weeks after surgery. | ||
14 | 1996 | Chronic Ambulatory Peritoneal Dialysis In A Patient With End Stage Renal Disease Following Radiotherapy And Surgery For Transitional Cell Carcinoma Click to View Abstract Renal transplantation is not readily available in the majority of countries in Africa. It is expensive and difficult to sustain on the meagre funds allocated to health. We report our short experience with fifteen living donor recipients followed in our unit for at least 24 months, range 26 - 48 (mean 35 months) post-transplantation. The donors and recipients were mostly young adults with mean ages of 36.7 years and 32.6 years respectively. The majority of the donors and recipients were males. The donors in most cases were siblings. Within this time, one graft has been lost at one year and the patient restarted on haemodialysis. Three patients died, two within the first year, the third at 23 months after transplantation, all with functioning grafts. The one year graft and patient survival rates were 93% and 86.6% respectively. The second year graft survival rates remained at 93% and the patients survival rate 80%. The nature and frequency of complications seen in these patients is comparable to those in other centres. Of all medical complications, bacterial infections contributed 69.4% of all infections. Cardiovascular complications comprised 31.25% of the complications. Hypertension seen in 85.5% of the patients accounted for 65% of the cardiovascular complications. Acute rejections were common and occurred in seven patients. Transplantation is a viable mode of renal replacement therapy (RRT) in our environment. The practice should be supported to make it more readily available to the many young end stage renal failure (ESRF) patients. | ||
15 | 1993 | Surgical Aspects Of Live Donor Kidney Transplants In Kenya Click to View Abstract Review of twenty cases of live-donor kidney transplants in Kenya for a period of 5 years (1985-1989) and the follow up study results revealed that there were both high graft losses, high morbidity and mortality due to various complications pertaining to surgery and immunosuppression. The most serious complications were intercurrent infections, acute or chronic rejection, pulmonary embolism, steroid induced diabetes, pneumonia, and myocardial infarction. At the end of the first year follow up, there were only twelve graft patients alive. Magnetic Resonance Imaging (MRI) was not available for assessing the anatomical and functional behaviour of the transplanted kidneys. This would have assisted in early diagnosis of the degree and onset of rejection for appropriate treatment before the death of the allografts. It would also assist in differentiating perfusional problems from rejection. | ||
16 | 1992 | Phaeochromocytoma:14 Cases Seen And Treated At Kenyatta National Hospital (5years) Click to View Abstract A study of 14 proven cases of phaeochromocytoma operated on at the Kenyatta National Hosspital was done.The management problems and the difficulty in diagnosis is disscussed | ||
17 | 1991 | Nurses Are Key Players. Click to View Abstract Review of twenty cases of live-donor kidney transplants in Kenya for a period of 5 years (1985-1989) and the follow up study results revealed that there were both high graft losses, high morbidity and mortality due to various complications pertaining to surgery and immunosuppression. The most serious complications were intercurrent infections, acute or chronic rejection, pulmonary embolism, steroid induced diabetes, pneumonia, and myocardial infarction. At the end of the first year follow up, there were only twelve graft patients alive. Magnetic Resonance Imaging (MRI) was not available for assessing the anatomical and functional behaviour of the transplanted kidneys. This would have assisted in early diagnosis of the degree and onset of rejection for appropriate treatment before the death of the allografts. It would also assist in differentiating perfusional problems from rejection. | ||
18 | 1990 | The AIDS Situation And Its Containment Click to View Abstract No abstract available yet | ||
19 | 1988 | One Stage Repair Of Urethral Strictures At The Kenyatta National Hospital (1978-1984). Click to View Abstract No abstract available yet | ||
20 | 1985 | Primary Hyperparathytodism At KNH Assoc. Of Surgeons Of E.A. Proceedings Dec. 1985 Click to View Abstract No abstract available yet | ||
21 | 1985 | Ureteric Injuries At KNH (6 Years Experience) Assoc. Of Surgeons Of E.A. Proceedings Dec. 1985 Click to View Abstract No abstract yet | ||
22 | 1985 | The Use Of Fine Needle Aspiration In Urological Practice Medicom 1985 Click to View Abstract No abstract yet | ||
23 | 1982 | Indwelling Catheter And Catheter Induced Infections Assoc. Of Surgeons Of E.A. Proceedings Dec. 1982 Click to View Abstract NoSUMMARY. A study of patients at St Peter’s Group of Hospitals,(Central London), University of London,and at Kenyatta National Hospital,University of Nairobi who had indwelling catheters for various reasons was done to compare the rates of catheter-induced infections in relation to the type/make,size fenestration or not and duration of stay in situ. | ||
24 | 1982 | Carcinoma Of Prostrate Management Assoc. Of Surgeons Of E.A. Proceedings Click to View Abstract No abstract yet | ||
25 | 1982 | Training Of A Urological Surgeon Click to View Abstract
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26 | 1980 | A Review F Thyroid Cancer At KNH. Medicom Vol. 2:3, 1980. Click to View Abstract No ABSTRACT. This a report of thirty patients who presented at Kenyatta National Hospital( KNH),Uinversity Of Nairobi (UON) during the three year period January 1974-December 1976 with a diagnosis of thyroid carcinoma.Fourteen had follicular, eight papiilary,four anaplastic,and four medullary types. | ||
27 | 1980 | Male Infertility At KNH. Medicom Vol. 2:95, 1980 Click to View Abstract No a ABSTRACT. | ||
28 | 1980 | Parathyroid Gland Tumour (case Report). Medicom 1:27, 1980 Click to View Abstract No abstract yet | ||
29 | 1980 | Training Of A Surgeon (Editorial) Medicom Vol. 2:25, 1980 Click to View Abstract No abstract yet | ||
30 | 1980 | Thyroid Enlargement And The Trachea ASEA Proceedings, 1980 Click to View Abstract ABSTRACT. | ||
31 | 1979 | Pyogenic Thyroiditis At KNH. E.A. Med. J. VOl. 56 No. 1, 1979 Click to View Abstract No abstract yet SUMMARY. Although pyogenic thyroiditis is rare,the four cases have been seen and treated at Kenyatta National Hospital (KNH) over the last 10 years.This is a report of one of these cases detailing the clinical presentation and operative findings. | ||
32 | 1979 | Case Report Of Pyogenic Thyroiditis At Kenyatta National Hospital. Click to View Abstract No abstract available yet. | ||
33 | 1978 | Carcinoma Of Thyroid At KNH Assoc. Of Surgeons Of E.A. Proceedings Dec. 1978 Click to View Abstract No abstract available yet.ABSTRACT. This a report of thirty patients who presented at Kenyatta National Hospital( KNH),Uinversity Of Nairobi (UON) during the three year period January 1974-December 1976 with a diagnosis of thyroid carcinoma.Fourteen had follicular, eight papiilary,four anaplastic,and four medullary types. | ||
34 | 1978 | Urethral Strictures, Treatment By One Stage Urethroplasty. (press) Click to View Abstract No abstract available yet. | ||
35 | 1977 | Intravenous Feeding In General Surgery. E.A. Med. J. Vol. 54 No. 1, 1977 Click to View Abstract No abstract yet. | ||
36 | 1977 | Thyrotoxicosis At Kenyatta National Hospital Nairobi.East Afr Med J. 1977 Oct;54(10):561-4. Click to View Abstract ABSTRAC |
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